Simple Search Results

Query String: METHICILLIN

Methicillin Staphcillin BDBM50103523 CHEBI:6827 Meticillin
sodium (2S,5R,6R)-6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate sodium 6beta-(2,6-dimethoxybenzamido)-2,2-dimethylpenam-3alpha-carboxylate BDBM50130829 Meticillin sodium salt methicillin sodium sodium 6beta-(2,6-dimethoxybenzamido)penicillanate CHEMBL1164 Meticillin sodium Dimocillin sodium

Lemaire, S; Glupczynski, Y; Duval, V; Joris, B; Tulkens, PM; Van Bambeke, F Activities of ceftobiprole and other cephalosporins against extracellular and intracellular (THP-1 macrophages and keratinocytes) forms of methicillin-susceptible and methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother 53: 2289-97 (2009)
Jin, J; Cui, J; Chaudhary, AS; Hsieh, YH; Damera, K; Zhang, H; Yang, H; Wang, B; Tai, PC Evaluation of small molecule SecA inhibitors against methicillin-resistant Staphylococcus aureus. Bioorg Med Chem 23: 7061-8 (2015)
Kim, HY; Wiles, JA; Wang, Q; Pais, GC; Lucien, E; Hashimoto, A; Nelson, DM; Thanassi, JA; Podos, SD; Deshpande, M; Pucci, MJ; Bradbury, BJ Exploration of the activity of 7-pyrrolidino-8-methoxyisothiazoloquinolones against methicillin-resistant Staphylococcus aureus (MRSA). J Med Chem 54: 3268-82 (2011)
Vorasin, O; Momphanao, K; Katrun, P; Kuhakarn, C; Jiarpinitnun, C Antibacterial activity evaluation of vinyl sulfones against global predominant methicillin-resistant Staphylococcus aureus USA300. Bioorg Med Chem Lett 63: (2022)
Llarrull, LI; Fisher, JF; Mobashery, S Molecular basis and phenotype of methicillin resistance in Staphylococcus aureus and insights into new beta-lactams that meet the challenge. Antimicrob Agents Chemother 53: 4051-63 (2009)
Koga, T; Masuda, N; Kakuta, M; Namba, E; Sugihara, C; Fukuoka, T Potent in vitro activity of tomopenem (CS-023) against methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa. Antimicrob Agents Chemother 52: 2849-54 (2008)
Elsebaei, MM; Mohammad, H; Abouf, M; Abutaleb, NS; Hegazy, YA; Ghiaty, A; Chen, L; Zhang, J; Malwal, SR; Oldfield, E; Seleem, MN; Mayhoub, AS Alkynyl-containing phenylthiazoles: Systemically active antibacterial agents effective against methicillin-resistant Staphylococcus aureus (MRSA). Eur J Med Chem 148: 195-209 (2018)
Abdeen, S; Kunkle, T; Salim, N; Ray, AM; Mammadova, N; Summers, C; Stevens, M; Ambrose, AJ; Park, Y; Schultz, PG; Horwich, AL; Hoang, QQ; Chapman, E; Johnson, SM Sulfonamido-2-arylbenzoxazole GroEL/ES Inhibitors as Potent Antibacterials against Methicillin-Resistant Staphylococcus aureus (MRSA). J Med Chem 61: 7345-7357 (2018)
Wei, H; Mao, F; Ni, S; Chen, F; Li, B; Qiu, X; Hu, L; Wang, M; Zheng, X; Zhu, J; Lan, L; Li, J Discovery of novel piperonyl derivatives as diapophytoene desaturase inhibitors for the treatment of methicillin-, vancomycin- and linezolid-resistant Staphylococcus aureus infections. Eur J Med Chem 145: 235-251 (2018)
Samir, M; Ramadan, M; Abdelrahman, MH; Elbastawesy, MAI; Halby, HM; Abdel-Aziz, M; Abuo-Rahma, GEA New potent ciprofloxacin-uracil conjugates as DNA gyrase and topoisomerase IV inhibitors against methicillin-resistant Staphylococcus aureus. Bioorg Med Chem 73: (2022)
Chung, M; Antignac, A; Kim, C; Tomasz, A Comparative study of the susceptibilities of major epidemic clones of methicillin-resistant Staphylococcus aureus to oxacillin and to the new broad-spectrum cephalosporin ceftobiprole. Antimicrob Agents Chemother 52: 2709-17 (2008)
Lim, CSQ; Ha, KP; Clarke, RS; Gavin, LA; Cook, DT; Hutton, JA; Sutherell, CL; Edwards, AM; Evans, LE; Tate, EW; Lanyon-Hogg, T Identification of a potent small-molecule inhibitor of bacterial DNA repair that potentiates quinolone antibiotic activity in methicillin-resistant Staphylococcus aureus. Bioorg Med Chem 27: (2019)
Zoraghi, R; Campbell, S; Kim, C; Dullaghan, EM; Blair, LM; Gillard, RM; Reiner, NE; Sperry, J Discovery of a 1,2-bis(3-indolyl)ethane that selectively inhibits the pyruvate kinase of methicillin-resistant Staphylococcus aureus over human isoforms. Bioorg Med Chem Lett 24: 5059-62 (2014)
Kumar, NS; Amandoron, EA; Cherkasov, A; Finlay, BB; Gong, H; Jackson, L; Kaur, S; Lian, T; Moreau, A; Labrière, C; Reiner, NE; See, RH; Strynadka, NC; Thorson, L; Wong, EW; Worrall, L; Zoraghi, R; Young, RN Optimization and structure-activity relationships of a series of potent inhibitors of methicillin-resistant Staphylococcus aureus (MRSA) pyruvate kinase as novel antimicrobial agents. Bioorg Med Chem 20: 7069-82 (2012)
Wang, Y; Di, H; Chen, F; Xu, Y; Xiao, Q; Wang, X; Wei, H; Lu, Y; Zhang, L; Zhu, J; Lan, L; Li, J Discovery of Benzocycloalkane Derivatives Efficiently Blocking Bacterial Virulence for the Treatment of Methicillin-Resistant S. aureus (MRSA) Infections by Targeting Diapophytoene Desaturase (CrtN). J Med Chem 59: 4831-48 (2016)
Wang, Y; Chen, F; Di, H; Xu, Y; Xiao, Q; Wang, X; Wei, H; Lu, Y; Zhang, L; Zhu, J; Sheng, C; Lan, L; Li, J Discovery of Potent Benzofuran-Derived Diapophytoene Desaturase (CrtN) Inhibitors with Enhanced Oral Bioavailability for the Treatment of Methicillin-Resistant Staphylococcus aureus (MRSA) Infections. J Med Chem 59: 3215-30 (2016)
Ni, S; Wei, H; Li, B; Chen, F; Liu, Y; Chen, W; Xu, Y; Qiu, X; Li, X; Lu, Y; Liu, W; Hu, L; Lin, D; Wang, M; Zheng, X; Mao, F; Zhu, J; Lan, L; Li, J Novel Inhibitors of Staphyloxanthin Virulence Factor in Comparison with Linezolid and Vancomycin versus Methicillin-Resistant, Linezolid-Resistant, and Vancomycin-Intermediate Staphylococcus aureus Infections in Vivo. J Med Chem 60: 8145-8159 (2017)
Wiles, JA; Song, Y; Wang, Q; Lucien, E; Hashimoto, A; Cheng, J; Marlor, CW; Ou, Y; Podos, SD; Thanassi, JA; Thoma, CL; Deshpande, M; Pucci, MJ; Bradbury, BJ Biological evaluation of isothiazoloquinolones containing aromatic heterocycles at the 7-position: In vitro activity of a series of potent antibacterial agents that are effective against methicillin-resistant Staphylococcus aureus. Bioorg Med Chem Lett 16: 1277-81 (2006)